The chemical imbalance theory of depression is dead – but that doesn’t mean antidepressants don’t work | Christopher Davey

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The chemical imbalance theory of depression is well and truly dead. A paper by Joanna Moncrieff and colleagues, longtime critics of the effectiveness of antidepressants, has caused a splash. The paper provides a summary of other summaries that confirm there is no evidence to support the idea that depression is caused by disturbance of the brain’s serotonin system. They have done us a favour by ...

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